Studies on Swine Dysentery

Experimental swine dysentery: comparison between infection models.

The aim of the present study was to develop a reproducible porcine infection model with Brachyspira hyodysenteriae. The influence of different factors was evaluated, namely, age, a diet containing large quantities of soybean meal, housing and administration of cortisol or antacids. Furthermore, the synergistic effect of additional bacteria (Escherichia coli O141, Bacteroides vulgatus or a mixtu...

Prevention of Swine Dysentery with Fitobiotics

An effective method was elaborated for extracting the active substances from commercially available Garden thyme and carob seeds. The antibacterial activity of dilutions of thyme and carob extracts and their combinations were studied by taking the minimum inhibitory concentrations (MIC) with agar well diffusion technique. The most effective concentrations of the two herb extracts were used for ...

A reverse vaccinology approach to swine dysentery vaccine development.

Swine dysentery (SD) is a mucohaemorrhagic colitis of pigs resulting from infection of the large intestine with the anaerobic intestinal spirochaete Brachyspira hyodysenteriae. Whole-cell bacterin vaccines are available to help control SD, but their performance has been inconsistent. This study aimed to use a reverse vaccinology approach to identify B. hyodysenteriae proteins for use as recombi...

Cytogenetical studies on swine intersexes.

Studies on the Flexner Group of Dysentery Bacilli

1. Volunteers have been immunized with the purified specific antigen of Type V Shigella paradysenteriae (Flexner). The subjects developed a high titer of bacterial agglutinins and mouse-protective antibodies. The agglutinin titer fell moderately after a period of 6 months. The subjects responded fairly well to a small recall dose of the antigen. 2. Two individuals from a group of 10 injected wi...